Skin prick tests to multiple pollens and prevalence of IgE specific to profilin

نویسندگان

  • Greg Plunkett
  • Domingo Barber
  • Eliseo M Villalobos
  • Joshua S Jacobs
  • Jeffrey S Hallett
  • Tara Mostofi
  • Agustin Galan Nieto
  • Tricia Moore
چکیده

Background Panallergens like profilin are proteins that have very similar sequences and structure. People can develop IgE specific to these highly cross reactive panallergens. The purpose of this study was to determine the prevalence of profilin sensitivity and the contribution to multiple allergen skin test responses. Sensitivity to profilin was established by IgE binding to purified profilins. Possible effects on skin test results were studied by including Queen Palm (QP) allergen in the skin prick testing panel as a possible source of profilin. QP is a species with a low probability of pollen exposure.

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عنوان ژورنال:

دوره 10  شماره 

صفحات  -

تاریخ انتشار 2014